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Balance between Coiled-Coil Stability and Dynamics Regulates Activity of BvgS Sensor Kinase in Bordetella

The two-component system BvgAS controls the expression of the virulence regulon of Bordetella pertussis. BvgS is a prototype of bacterial sensor kinases with extracytoplasmic Venus flytrap perception domains. Following its transmembrane segment, BvgS harbors a cytoplasmic Per-Arnt-Sim (PAS) domain a...

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Detalles Bibliográficos
Autores principales: Lesne, E., Krammer, E.-M., Dupre, E., Locht, C., Lensink, M. F., Antoine, R., Jacob-Dubuisson, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810494/
https://www.ncbi.nlm.nih.gov/pubmed/26933056
http://dx.doi.org/10.1128/mBio.02089-15