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Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing
During cryopreservation, ice recrystallization is a major cause of cellular damage. Conventional cryoprotectants such as dimethyl sulfoxide (DMSO) and glycerol function by a number of different mechanisms but do not mitigate or control ice recrystallization at concentrations utilized in cryopreserva...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810524/ https://www.ncbi.nlm.nih.gov/pubmed/27021850 http://dx.doi.org/10.1038/srep23619 |