Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing

During cryopreservation, ice recrystallization is a major cause of cellular damage. Conventional cryoprotectants such as dimethyl sulfoxide (DMSO) and glycerol function by a number of different mechanisms but do not mitigate or control ice recrystallization at concentrations utilized in cryopreserva...

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Detalles Bibliográficos
Autores principales: Briard, Jennie G., Poisson, Jessica S., Turner, Tracey R., Capicciotti, Chantelle J., Acker, Jason P., Ben, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810524/
https://www.ncbi.nlm.nih.gov/pubmed/27021850
http://dx.doi.org/10.1038/srep23619

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