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Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor

The receptor(s) for porcine sapelovirus (PSV), which causes diarrhea, pneumonia, polioencephalomyelitis, and reproductive disorders in pigs, remains largely unknown. Given the precedent for other picornaviruses which use terminal sialic acids (SAs) as receptors, we examined the role of SAs in PSV bi...

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Detalles Bibliográficos
Autores principales: Kim, Deok-Song, Son, Kyu-Yeol, Koo, Kyung-Min, Kim, Ji-Yun, Alfajaro, Mia Madel, Park, Jun-Gyu, Hosmillo, Myra, Soliman, Mahmoud, Baek, Yeong-Bin, Cho, Eun-Hyo, Lee, Ju-Hwan, Kang, Mun-Il, Goodfellow, Ian, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810533/
https://www.ncbi.nlm.nih.gov/pubmed/26865725
http://dx.doi.org/10.1128/JVI.02449-15