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ISC, a Novel Group of Bacterial and Archaeal DNA Transposons That Encode Cas9 Homologs
Bacterial genomes encode numerous homologs of Cas9, the effector protein of the type II CRISPR-Cas systems. The homology region includes the arginine-rich helix and the HNH nuclease domain that is inserted into the RuvC-like nuclease domain. These genes, however, are not linked to cas genes or CRISP...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810608/ https://www.ncbi.nlm.nih.gov/pubmed/26712934 http://dx.doi.org/10.1128/JB.00783-15 |