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Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain

Notch signalling is a well-established pathway that regulates neurogenesis. However, little is known about the role of Notch signalling in specific neuronal differentiation. Using Dll1 null mice, we found that Notch signalling has no function in the specification of mesencephalic dopaminergic neural...

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Detalles Bibliográficos
Autores principales: Trujillo-Paredes, Niurka, Valencia, Concepción, Guerrero-Flores, Gilda, Arzate, Dulce-María, Baizabal, José-Manuel, Guerra-Crespo, Magdalena, Fuentes-Hernández, Ayari, Zea-Armenta, Iván, Covarrubias, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810735/
https://www.ncbi.nlm.nih.gov/pubmed/26912775
http://dx.doi.org/10.1242/bio.013383