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Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells

BACKGROUND: Hypoxia-tolerant human glioma cells reduce oxygen consumption rate in response to oxygen deficit, a defense mechanism that contributes to survival under moderately hypoxic conditions. In contrast, hypoxia-sensitive cells lack this ability. As it has been previously shown that hypoxia-tol...

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Detalles Bibliográficos
Autores principales: DeHaan, Carrie, Habibi-Nazhad, Bahram, Yan, Elizabeth, Salloum, Nicole, Parliament, Matthew, Allalunis-Turner, Joan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC481082/
https://www.ncbi.nlm.nih.gov/pubmed/15248896
http://dx.doi.org/10.1186/1476-4598-3-19