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Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells
BACKGROUND: Hypoxia-tolerant human glioma cells reduce oxygen consumption rate in response to oxygen deficit, a defense mechanism that contributes to survival under moderately hypoxic conditions. In contrast, hypoxia-sensitive cells lack this ability. As it has been previously shown that hypoxia-tol...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC481082/ https://www.ncbi.nlm.nih.gov/pubmed/15248896 http://dx.doi.org/10.1186/1476-4598-3-19 |