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Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets

Objectives. After development and differentiation, megakaryocytes (MKs) can produce platelets. As is well known, thrombopoietin (TPO) can induce MKs to differentiate. The effect of thrombin on MKs differentiation is not clear. In this study, we used a human megakaryoblastic leukemia cell line (Meg-0...

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Detalles Bibliográficos
Autores principales: Yang, Xiao-Lei, Ge, Meng-Kai, Mao, De-Kui, Lv, Ying-Tao, Sun, Shu-Yan, Yu, Ai-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811061/
https://www.ncbi.nlm.nih.gov/pubmed/27064425
http://dx.doi.org/10.1155/2016/9313269