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Short hairpin RNA targeting insulin-like growth factor binding protein-3 restores the bioavailability of insulin-like growth factor-1 in diabetic rats

PURPOSE: To investigate whether intracavernosal injection of short hairpin RNA for IGFBP-3 could improve erectile function in streptozotocin-induced diabetic rats. MATERIALS AND METHODS: After 12 weeks of IGFBP-3 short hairpin RNA injection treatment, intracavernous pressure responses to electrical...

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Detalles Bibliográficos
Autores principales: Zhou, Zhang-Yan, Zhong, Guang-Jun, Cheng, Shao-Ping, Huang, Hui, Wang, Jing, Pan, Hui, Liu, Chang-Mao, Xing, Cheng, Sun, Ya-Ling, Liu, Rong-Hua, Fei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Urologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811239/
https://www.ncbi.nlm.nih.gov/pubmed/27136480
http://dx.doi.org/10.1590/S1677-5538.IBJU.2014.0416