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Anticancer effect of metformin on estrogen receptor-positive and tamoxifen-resistant breast cancer cell lines
Acquisition of tamoxifen resistance (TR) during anti-estrogenic therapy using tamoxifen is a major obstacle in the treatment of estrogen receptor (ER)-positive breast cancer. As a biguanide derivative, metformin is commonly used to treat type II diabetes. It has recently emerged as a potential antic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811404/ https://www.ncbi.nlm.nih.gov/pubmed/26986571 http://dx.doi.org/10.3892/or.2016.4675 |