Cargando…

Anticancer effect of metformin on estrogen receptor-positive and tamoxifen-resistant breast cancer cell lines

Acquisition of tamoxifen resistance (TR) during anti-estrogenic therapy using tamoxifen is a major obstacle in the treatment of estrogen receptor (ER)-positive breast cancer. As a biguanide derivative, metformin is commonly used to treat type II diabetes. It has recently emerged as a potential antic...

Descripción completa

Detalles Bibliográficos
Autores principales: KIM, JINKYOUNG, LEE, JIYUN, JANG, SOON YOUNG, KIM, CHUNGYEUL, CHOI, YOOJIN, KIM, AEREE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811404/
https://www.ncbi.nlm.nih.gov/pubmed/26986571
http://dx.doi.org/10.3892/or.2016.4675