Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine

Ezetimibe inhibits Niemann-Pick C1-like 1 (NPC1L1), an apical membrane cholesterol transporter of enterocytes, thereby reduces intestinal cholesterol absorption. This treatment also increases extrahepatic reverse cholesterol transport via an undefined mechanism. To explore this, we employed a trans-...

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Detalles Bibliográficos
Autores principales: Nakano, Takanari, Inoue, Ikuo, Takenaka, Yasuhiro, Ono, Hiraku, Katayama, Shigehiro, Awata, Takuya, Murakoshi, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811413/
https://www.ncbi.nlm.nih.gov/pubmed/27023132
http://dx.doi.org/10.1371/journal.pone.0152207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811413/
https://www.ncbi.nlm.nih.gov/pubmed/27023132
http://dx.doi.org/10.1371/journal.pone.0152207

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