Cargando…

Intercellular Protein Transfer from Thymocytes to Thymic Epithelial Cells

Promiscuous expression of tissue restricted antigens (TRAs) in medullary thymic epithelial cells (mTECs) is crucial for negative selection of self-reactive T cells to establish central tolerance. Intercellular transfer of self-peptide-MHC complexes from mTECs to thymic dendritic cells (DCs) allows D...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hong-Xia, Qiu, Yu-Rong, Zhong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811443/
https://www.ncbi.nlm.nih.gov/pubmed/27022746
http://dx.doi.org/10.1371/journal.pone.0152641