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The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

The protein kinase LKB1 regulates cell metabolism and growth and is implicated in intestinal and lung cancer. Bone morphogenetic protein (BMP) signaling regulates cell differentiation during development and tissue homeostasis. We demonstrate that LKB1 physically interacts with BMP type I receptors a...

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Detalles Bibliográficos
Autores principales: Raja, Erna, Tzavlaki, Kalliopi, Vuilleumier, Robin, Edlund, Karolina, Kahata, Kaoru, Zieba, Agata, Morén, Anita, Watanabe, Yukihide, Voytyuk, Iryna, Botling, Johan, Söderberg, Ola, Micke, Patrick, Pyrowolakis, George, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811448/
https://www.ncbi.nlm.nih.gov/pubmed/26701726