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The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling
The protein kinase LKB1 regulates cell metabolism and growth and is implicated in intestinal and lung cancer. Bone morphogenetic protein (BMP) signaling regulates cell differentiation during development and tissue homeostasis. We demonstrate that LKB1 physically interacts with BMP type I receptors a...
Autores principales: | Raja, Erna, Tzavlaki, Kalliopi, Vuilleumier, Robin, Edlund, Karolina, Kahata, Kaoru, Zieba, Agata, Morén, Anita, Watanabe, Yukihide, Voytyuk, Iryna, Botling, Johan, Söderberg, Ola, Micke, Patrick, Pyrowolakis, George, Heldin, Carl-Henrik, Moustakas, Aristidis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811448/ https://www.ncbi.nlm.nih.gov/pubmed/26701726 |
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