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Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity

Breast cancer stem cells (BCSCs) play crucial roles in tumor initiation, metastasis and therapeutic resistance. A strict dependency between BCSCs and stromal cell components of tumor microenvironment exists. Thus, novel therapeutic strategies aimed to target the crosstalk between activated microenvi...

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Detalles Bibliográficos
Autores principales: Giordano, Cinzia, Chemi, Francesca, Panza, Salvatore, Barone, Ines, Bonofiglio, Daniela, Lanzino, Marilena, Cordella, Angela, Campana, Antonella, Hashim, Adnan, Rizza, Pietro, Leggio, Antonella, Győrffy, Balázs, Simões, Bruno M., Clarke, Robert B., Weisz, Alessandro, Catalano, Stefania, Andò, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811458/
https://www.ncbi.nlm.nih.gov/pubmed/26556856