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Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma

In most myeloma patients, even after several rounds of intensive therapy, drug resistant tumor cells survive and proliferate aggressively leading to relapse. In the present study, gene expression profiling of tumor cells isolated from myeloma patients after sequential rounds of chemotherapy, reveale...

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Detalles Bibliográficos
Autores principales: Ramani, Vishnu C., Zhan, Fenghuang, He, Jianbo, Barbieri, Paola, Noseda, Alessandro, Tricot, Guido, Sanderson, Ralph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811483/
https://www.ncbi.nlm.nih.gov/pubmed/26624982