Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation

Nasopharyngeal carcinoma (NPC) is a common head and neck malignancy without efficient chemotherapeutic agents for it. In our current study, we demonstrated the cytotoxicity effects of a newly patented compound temozolomide–perillyl alcohol (TMZ-POH) on NPC in vitro and in vivo, and the possible mech...

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Detalles Bibliográficos
Autores principales: Xie, Li, Song, Xingguo, Guo, Wei, Wang, Xingwu, Wei, Ling, Li, Yang, Lv, Liyan, Wang, Weijun, Chen, Thomas C., Song, Xianrang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811487/
https://www.ncbi.nlm.nih.gov/pubmed/26625208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811487/
https://www.ncbi.nlm.nih.gov/pubmed/26625208

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