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Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model

INTRODUCTION: Breast cancer, the product of numerous rare mutational events that occur over an extended time period, presents numerous challenges to investigators interested in studying the transformation from normal breast epithelium to malignancy using traditional laboratory methods, particularly...

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Detalles Bibliográficos
Autores principales: Chapa, Joaquin, An, Gary, Kulkarni, Swati A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811527/
https://www.ncbi.nlm.nih.gov/pubmed/27023391
http://dx.doi.org/10.1371/journal.pone.0152298