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Impact of 3-Amino-1,2,4-Triazole (3-AT)-Derived Increase in Hydrogen Peroxide Levels on Inflammation and Metabolism in Human Differentiated Adipocytes

Obesity is characterized by an excessive accumulation of fat in adipose tissue, which is associated with oxidative stress and chronic inflammation. Excessive H(2)O(2) levels are degraded by catalase (CAT), the activity of which is decreased in obesity. We investigated the effects of inhibition of ca...

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Detalles Bibliográficos
Autores principales: Ruiz-Ojeda, Francisco Javier, Gomez-Llorente, Carolina, Aguilera, Concepción María, Gil, Angel, Rupérez, Azahara Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811533/
https://www.ncbi.nlm.nih.gov/pubmed/27023799
http://dx.doi.org/10.1371/journal.pone.0152550