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Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 Signaling

Clinical studies have identified hypoadiponectinemia as an independent hypertension risk factor. It is known that adiponectin (APN) can directly cause vasodilation, but the doses required exceed physiologic levels several fold. In the current study, we determine the effect of physiologically relevan...

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Detalles Bibliográficos
Autores principales: Du, Yunhui, Li, Rui, Lau, Wayne Bigond, Zhao, Jianli, Lopez, Bernard, Christopher, Theodore A., Ma, Xin-Liang, Wang, Yajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811582/
https://www.ncbi.nlm.nih.gov/pubmed/27023866
http://dx.doi.org/10.1371/journal.pone.0152247