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Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 Signaling
Clinical studies have identified hypoadiponectinemia as an independent hypertension risk factor. It is known that adiponectin (APN) can directly cause vasodilation, but the doses required exceed physiologic levels several fold. In the current study, we determine the effect of physiologically relevan...
Autores principales: | Du, Yunhui, Li, Rui, Lau, Wayne Bigond, Zhao, Jianli, Lopez, Bernard, Christopher, Theodore A., Ma, Xin-Liang, Wang, Yajing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811582/ https://www.ncbi.nlm.nih.gov/pubmed/27023866 http://dx.doi.org/10.1371/journal.pone.0152247 |
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