Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases

Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass in sheep. The objectives were to investigate whether myostatin gene can be edited in sheep by transc...

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Detalles Bibliográficos
Autores principales: Zhao, Xinxia, Ni, Wei, Chen, Chuangfu, Sai, Wujiafu, Qiao, Jun, Sheng, Jingliang, Zhang, Hui, Li, Guozhong, Wang, Dawei, Hu, Shengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811794/
https://www.ncbi.nlm.nih.gov/pubmed/26950874
http://dx.doi.org/10.5713/ajas.15.0041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811794/
https://www.ncbi.nlm.nih.gov/pubmed/26950874
http://dx.doi.org/10.5713/ajas.15.0041

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