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EM Adaptive LASSO—A Multilocus Modeling Strategy for Detecting SNPs Associated with Zero-inflated Count Phenotypes

Count data are increasingly ubiquitous in genetic association studies, where it is possible to observe excess zero counts as compared to what is expected based on standard assumptions. For instance, in rheumatology, data are usually collected in multiple joints within a person or multiple sub-region...

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Detalles Bibliográficos
Autores principales: Mallick, Himel, Tiwari, Hemant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811966/
https://www.ncbi.nlm.nih.gov/pubmed/27066062
http://dx.doi.org/10.3389/fgene.2016.00032