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Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays

The recent availability of human induced pluripotent stem cells (hiPSCs) holds great promise as a novel source of human-derived neurons for cell and tissue therapies as well as for in vitro drug screenings that might replace the use of animal models. However, there is still a considerable lack of kn...

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Detalles Bibliográficos
Autores principales: Amin, Hayder, Maccione, Alessandro, Marinaro, Federica, Zordan, Stefano, Nieus, Thierry, Berdondini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811967/
https://www.ncbi.nlm.nih.gov/pubmed/27065786
http://dx.doi.org/10.3389/fnins.2016.00121