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Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans

OBJECTIVE: Circulating long-chain free fatty acids (FFAs) are important metabolic signals that acutely enhance fatty acid oxidation, thermogenesis, energy expenditure, and insulin secretion. However, if chronically elevated, they provoke inflammation, insulin resistance, and β-cell failure. Moreover...

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Detalles Bibliográficos
Autores principales: Ordelheide, Anna-Maria, Gommer, Nadja, Böhm, Anja, Hermann, Carina, Thielker, Inga, Machicao, Fausto, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812007/
https://www.ncbi.nlm.nih.gov/pubmed/27069870
http://dx.doi.org/10.1016/j.molmet.2016.02.001