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Circulating Human Neonatal Naïve B Cells are Deficient in CD73 Impairing Purine Salvage

BACKGROUND: Extracellular purines, in particular adenosine (Ado) and adenosine-triphosphate, are critical immunoregulatory molecules. Expression and activity of purine ecto-enzymes on B cells in neonatal and adult blood may influence their function and has been incompletely characterized. METHODS: M...

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Detalles Bibliográficos
Autores principales: Pettengill, Matthew Aaron, Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812068/
https://www.ncbi.nlm.nih.gov/pubmed/27066009
http://dx.doi.org/10.3389/fimmu.2016.00121