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Circulating Human Neonatal Naïve B Cells are Deficient in CD73 Impairing Purine Salvage
BACKGROUND: Extracellular purines, in particular adenosine (Ado) and adenosine-triphosphate, are critical immunoregulatory molecules. Expression and activity of purine ecto-enzymes on B cells in neonatal and adult blood may influence their function and has been incompletely characterized. METHODS: M...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812068/ https://www.ncbi.nlm.nih.gov/pubmed/27066009 http://dx.doi.org/10.3389/fimmu.2016.00121 |