Flavonolignans As a Novel Class of Sodium Pump Inhibitors

We examined the inhibitory effects of three flavonolignans and their dehydro- derivatives, taxifolin and quercetin on the activity of the Na(+)/K(+)-ATPase (NKA). The flavonolignans silychristin, dehydrosilychristin and dehydrosilydianin inhibited NKA with IC(50) of 110 ± 40 μM, 38 ± 8 μM, and 36 ±...

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Detalles Bibliográficos
Autores principales: Kubala, Martin, Čechová, Petra, Geletičová, Jaroslava, Biler, Michal, Štenclová, Tereza, Trouillas, Patrick, Biedermann, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812144/
https://www.ncbi.nlm.nih.gov/pubmed/27065883
http://dx.doi.org/10.3389/fphys.2016.00115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812144/
https://www.ncbi.nlm.nih.gov/pubmed/27065883
http://dx.doi.org/10.3389/fphys.2016.00115

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