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Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells
Glioblastoma is the most common and most aggressive brain tumor in adults. The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas, but it is not curative. The difficulties in treating glioblastoma may be as a result of the presence of glioma stem cells (GSCs), which a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812167/ https://www.ncbi.nlm.nih.gov/pubmed/27073554 http://dx.doi.org/10.3892/ol.2016.4315 |