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Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells

Glioblastoma is the most common and most aggressive brain tumor in adults. The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas, but it is not curative. The difficulties in treating glioblastoma may be as a result of the presence of glioma stem cells (GSCs), which a...

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Detalles Bibliográficos
Autores principales:	YU, ZHIYUN, ZHAO, GANG, LI, PENGLIANG, LI, YUNQIAN, ZHOU, GUANGTONG, CHEN, YONG, XIE, GUIFANG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812167/ https://www.ncbi.nlm.nih.gov/pubmed/27073554 http://dx.doi.org/10.3892/ol.2016.4315

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