Human cytomegalovirus gH stability and trafficking are regulated by ER-associated degradation and transmembrane architecture

The prototypic betaherpesvirus human cytomegalovirus (CMV) establishes life-long persistence within its human host. While benign in healthy individuals, CMV poses a significant threat to the immune compromised, including transplant recipients and neonates. The CMV glycoprotein complex gH/gL/gO media...

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Detalles Bibliográficos
Autores principales: Gardner, Thomas J., Hernandez, Rosmel E., Noriega, Vanessa M., Tortorella, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812245/
https://www.ncbi.nlm.nih.gov/pubmed/27026399
http://dx.doi.org/10.1038/srep23692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812245/
https://www.ncbi.nlm.nih.gov/pubmed/27026399
http://dx.doi.org/10.1038/srep23692

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