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Human cytomegalovirus gH stability and trafficking are regulated by ER-associated degradation and transmembrane architecture
The prototypic betaherpesvirus human cytomegalovirus (CMV) establishes life-long persistence within its human host. While benign in healthy individuals, CMV poses a significant threat to the immune compromised, including transplant recipients and neonates. The CMV glycoprotein complex gH/gL/gO media...
Autores principales: | Gardner, Thomas J., Hernandez, Rosmel E., Noriega, Vanessa M., Tortorella, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812245/ https://www.ncbi.nlm.nih.gov/pubmed/27026399 http://dx.doi.org/10.1038/srep23692 |
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