Adenosine receptor agonist NECA increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation

Conventional methods for therapeutic blood-brain barrier (BBB) disruption facilitate drug delivery but are cumbersome to perform. A previous study demonstrated that adenosine receptor (AR) stimulation by 5′-N-ethylcarboxamide adenosine (NECA) increased the extravasation of intravascular tracers into...

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Detalles Bibliográficos
Autores principales: Cheng, Chih-Chung, Yang, Ya Lan, Liao, Kate Hsiurong, Lai, Ted Weita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812297/
https://www.ncbi.nlm.nih.gov/pubmed/27025761
http://dx.doi.org/10.1038/srep23882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812297/
https://www.ncbi.nlm.nih.gov/pubmed/27025761
http://dx.doi.org/10.1038/srep23882

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