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Electric pulse current stimulation increases electrophysiological properties of I(f) current reconstructed in mHCN4-transfected canine mesenchymal stem cells

The ‘funny’ current, also known as the I(f) current, play a crucial role in the spontaneous diastolic depolarization of sinoatrial node cells. The I(f) current is primarily induced by the protein encoded by the hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) gene. The functional...

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Detalles Bibliográficos
Autores principales: FENG, YUANYUAN, LUO, SHOUMING, YANG, PAN, SONG, ZHIYUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812437/
https://www.ncbi.nlm.nih.gov/pubmed/27073443
http://dx.doi.org/10.3892/etm.2016.3072