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Targeted quantification of N-1-(carboxymethyl) valine and N-1-(carboxyethyl) valine peptides of β-hemoglobin for better diagnostics in diabetes

BACKGROUND: N-1-(Deoxyfructosyl) valine (DFV) β-hemoglobin (β-Hb), commonly referred as HbA1c, is widely used diagnostic marker in diabetes, believed to provide glycemic status of preceding 90–120 days. However, the turnover of hemoglobin is about 120 days, the DFV-β-Hb, an early and reversible glyc...

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Detalles Bibliográficos
Autores principales: Jagadeeshaprasad, Mashanipalya G., Batkulwar, Kedar B., Meshram, Nishita N., Tiwari, Shalbha, Korwar, Arvind M., Unnikrishnan, Ambika G., Kulkarni, Mahesh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812615/
https://www.ncbi.nlm.nih.gov/pubmed/27030792
http://dx.doi.org/10.1186/s12014-016-9108-y