CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo

BACKGROUND: CD4 T cell depletion during HIV-1 infection is associated with AIDS disease progression, and the HIV-1 Env protein plays an important role in the process. Together with CXCR4, CCR5 is one of the two co-receptors that interact with Env during virus entry, but the role of CCR5 in Env-induc...

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Detalles Bibliográficos
Autores principales: Tsao, Li-Chung, Guo, Haitao, Jeffrey, Jerry, Hoxie, James A., Su, Lishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812640/
https://www.ncbi.nlm.nih.gov/pubmed/27026376
http://dx.doi.org/10.1186/s12977-016-0255-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812640/
https://www.ncbi.nlm.nih.gov/pubmed/27026376
http://dx.doi.org/10.1186/s12977-016-0255-z

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