Discovery and characterization of a novel CCND1/MRCK gene fusion in mantle cell lymphoma

The t(11;14) translocation resulting in constitutive cyclin D1 expression is an early event in mantle cell lymphoma (MCL) transformation. Patients with a highly proliferative phenotype produce cyclin D1 transcripts with truncated 3′UTRs that evade miRNA regulation. Here, we report the recurrence of...

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Detalles Bibliográficos
Autores principales: Masamha, Chioniso Patience, Albrecht, Todd R., Wagner, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812644/
https://www.ncbi.nlm.nih.gov/pubmed/27025456
http://dx.doi.org/10.1186/s13045-016-0260-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812644/
https://www.ncbi.nlm.nih.gov/pubmed/27025456
http://dx.doi.org/10.1186/s13045-016-0260-7

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