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The role of cullin 5-containing ubiquitin ligases

The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5 (Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing proteins have ubiquitin ligase activity mediated by the formation of a complex with the scaffold protein Cul5 and the RING do...

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Detalles Bibliográficos
Autores principales: Okumura, Fumihiko, Joo-Okumura, Akiko, Nakatsukasa, Kunio, Kamura, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812663/
https://www.ncbi.nlm.nih.gov/pubmed/27030794
http://dx.doi.org/10.1186/s13008-016-0016-3