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Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones

BACKGROUND: Chinese hamster ovary (CHO) cells have become the host of choice for the production of recombinant proteins, due to their capacity for correct protein folding, assembly, and posttranslational modifications. The most widely used system for recombinant proteins is the gene amplification pr...

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Detalles Bibliográficos
Autores principales: Jamnikar, Uros, Nikolic, Petra, Belic, Ales, Blas, Marjanca, Gaser, Dominik, Francky, Andrej, Laux, Holger, Blejec, Andrej, Baebler, Spela, Gruden, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812793/
https://www.ncbi.nlm.nih.gov/pubmed/26499110
http://dx.doi.org/10.1186/s12896-015-0218-9