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Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones
BACKGROUND: Chinese hamster ovary (CHO) cells have become the host of choice for the production of recombinant proteins, due to their capacity for correct protein folding, assembly, and posttranslational modifications. The most widely used system for recombinant proteins is the gene amplification pr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812793/ https://www.ncbi.nlm.nih.gov/pubmed/26499110 http://dx.doi.org/10.1186/s12896-015-0218-9 |