Cargando…

Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones

BACKGROUND: Chinese hamster ovary (CHO) cells have become the host of choice for the production of recombinant proteins, due to their capacity for correct protein folding, assembly, and posttranslational modifications. The most widely used system for recombinant proteins is the gene amplification pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jamnikar, Uros, Nikolic, Petra, Belic, Ales, Blas, Marjanca, Gaser, Dominik, Francky, Andrej, Laux, Holger, Blejec, Andrej, Baebler, Spela, Gruden, Kristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812793/ https://www.ncbi.nlm.nih.gov/pubmed/26499110 http://dx.doi.org/10.1186/s12896-015-0218-9

Ejemplares similares

pISA-tree - a data management framework for life science research projects using a standardised directory tree
por: Petek, Marko, et al.
Publicado: (2022)

Dynamics of Responses in Compatible Potato - Potato virus Y Interaction Are Modulated by Salicylic Acid
por: Baebler, Špela, et al.
Publicado: (2011)

Precision transcriptomics of viral foci reveals the spatial regulation of immune‐signaling genes and identifies RBOHD as an important player in the incompatible interaction between potato virus Y and potato
por: Lukan, Tjaša, et al.
Publicado: (2020)

Plant Molecular Responses to Potato Virus Y: A Continuum of Outcomes from Sensitivity and Tolerance to Resistance
por: Baebler, Špela, et al.
Publicado: (2020)

Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation
por: Petek, Marko, et al.
Publicado: (2010)

'Bois noir' phytoplasma induces significant reprogramming of the leaf transcriptome in the field grown grapevine
por: Hren, Matjaž, et al.
Publicado: (2009)

Adaptation of the MapMan ontology to biotic stress responses: application in solanaceous species
por: Rotter, Ana, et al.
Publicado: (2007)

Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis
por: Blažič, Marko, et al.
Publicado: (2015)

DiNAR: revealing hidden patterns of plant signalling dynamics using Differential Network Analysis in R
por: Zagorščak, Maja, et al.
Publicado: (2018)

Potato virus Y infection hinders potato defence response and renders plants more vulnerable to Colorado potato beetle attack
por: Petek, Marko, et al.
Publicado: (2014)

Plant X-tender: An extension of the AssemblX system for the assembly and expression of multigene constructs in plants
por: Lukan, Tjaša, et al.
Publicado: (2018)

Bimodal dynamics of primary metabolism-related responses in tolerant potato-Potato virus Y interaction
por: Stare, Tjaša, et al.
Publicado: (2015)

Erratum to: Bimodal dynamics of primary metabolism-related responses in tolerant potato-Potato virus Y interaction
por: Stare, Tjaša, et al.
Publicado: (2017)

Reduction in C-terminal amidated species of recombinant monoclonal antibodies by genetic modification of CHO cells
por: Škulj, Mihaela, et al.
Publicado: (2014)

GoMapMan: integration, consolidation and visualization of plant gene annotations within the MapMan ontology
por: Ramšak, Živa, et al.
Publicado: (2014)

Involvement of Potato (Solanum tuberosum L.) MKK6 in Response to Potato virus Y
por: Lazar, Ana, et al.
Publicado: (2014)

Cell Death Is Not Sufficient for the Restriction of Potato Virus Y Spread in Hypersensitive Response-Conferred Resistance in Potato
por: Lukan, Tjaša, et al.
Publicado: (2018)

quantGenius: implementation of a decision support system for qPCR-based gene quantification
por: Baebler, Špela, et al.
Publicado: (2017)

Chloroplast redox state changes mark cell‐to‐cell signaling in the hypersensitive response
por: Lukan, Tjaša, et al.
Publicado: (2022)

Salicylic Acid Perturbs sRNA-Gibberellin Regulatory Network in Immune Response of Potato to Potato virus Y Infection
por: Križnik, Maja, et al.
Publicado: (2017)

Whole genome sequence and a phylogenetic analysis of the G8P[14] group A rotavirus strain from roe deer
por: Jamnikar-Ciglenecki, Urska, et al.
Publicado: (2017)

Transcriptional deregulation of stress-growth balance in Nicotiana benthamiana biofactories producing insect sex pheromones
por: Juteršek, Mojca, et al.
Publicado: (2022)

Identification of plasma biomarker candidates in glioblastoma using an antibody-array-based proteomic approach
por: Zupancic, Klemen, et al.
Publicado: (2014)

β-1,3-glucanase class III promotes spread of PVY(NTN) and improves in planta protein production
por: Dobnik, David, et al.
Publicado: (2013)

Retrovectors packaged in CHO cells to generate GLP-1-Fc stable expression CHO cell lines
por: Li, Jing, et al.
Publicado: (2019)

Influence of glutamine on transient and stable recombinant protein production in CHO and HEK-293 cells
por: Rajendra, Yashas, et al.
Publicado: (2011)

Stable overexpression of miR-17 enhances recombinant protein production of CHO cells()
por: Jadhav, Vaibhav, et al.
Publicado: (2014)

Analysis of Glioblastoma Patients' Plasma Revealed the Presence of MicroRNAs with a Prognostic Impact on Survival and Those of Viral Origin
por: Herman, Ana, et al.
Publicado: (2015)

Generation of genetically engineered CHO cell lines to support the production of a difficult to express therapeutic protein
por: Laux, Holger, et al.
Publicado: (2013)

Stable Expression of Recombinant Factor VIII in CHO Cells Using Methotrexate-Driven Transgene Amplification
por: Orlova, N. A., et al.
Publicado: (2012)

Food Safety Knowledge among Professional Food Handlers in Slovenia: The Results of a Nation-Wide Survey
por: Jevšnik, Mojca, et al.
Publicado: (2023)

TGA transcription factors—Structural characteristics as basis for functional variability
por: Tomaž, Špela, et al.
Publicado: (2022)

Detection and Whole-Genome Analysis of a Zoonotic G8P[14] Rotavirus Strain Isolated from a Child with Diarrhea
por: Steyer, Andrej, et al.
Publicado: (2017)

A molecular survey, whole genome sequencing and phylogenetic analysis of astroviruses from roe deer
por: Jamnikar-Ciglenecki, Urska, et al.
Publicado: (2020)

Establishment of a stable CHO cell line with high level expression of recombinant porcine IFN-β
por: Chen, Weiye, et al.
Publicado: (2011)

Development of a CHO cell line for stable production of recombinant antibodies against human MMP9
por: Ryu, Jina, et al.
Publicado: (2022)

Editorial: Women in plant pathogen interactions: 2022
por: Baebler, Špela, et al.
Publicado: (2023)

Engineering CHO cell growth by stable manipulation of miRNA expression
por: Sanchez, Noëlia, et al.
Publicado: (2011)

Recombinant hemagglutinin produced from Chinese Hamster Ovary (CHO) stable cell clones and a PELC/CpG combination adjuvant for H7N9 subunit vaccine development
por: Chen, Ting-Hsuan, et al.
Publicado: (2019)

Insect pest management in the age of synthetic biology
por: Mateos Fernández, Rubén, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9c0cp8g7il2ctuoqm03ho8dj1a