Optimal multiple testing under a Gaussian prior on the effect sizes

We develop a new method for large-scale frequentist multiple testing with Bayesian prior information. We find optimal [Formula: see text]-value weights that maximize the average power of the weighted Bonferroni method. Due to the nonconvexity of the optimization problem, previous methods that accoun...

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Detalles Bibliográficos
Autores principales: Dobriban, Edgar, Fortney, Kristen, Kim, Stuart K., Owen, Art B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813057/
https://www.ncbi.nlm.nih.gov/pubmed/27046938
http://dx.doi.org/10.1093/biomet/asv050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813057/
https://www.ncbi.nlm.nih.gov/pubmed/27046938
http://dx.doi.org/10.1093/biomet/asv050

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