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Metabolomic Profiling of Post-Mortem Brain Reveals Changes in Amino Acid and Glucose Metabolism in Mental Illness Compared with Controls

Metabolomic profiling was carried out on 53 post-mortem brain samples from subjects diagnosed with schizophrenia, depression, bipolar disorder (SDB), diabetes, and controls. Chromatography on a ZICpHILIC column was used with detection by Orbitrap mass spectrometry. Data extraction was carried out wi...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Zhang, Tong, Ali, Ali Muhsen, Al Washih, Mohammed, Pickard, Benjamin, Watson, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813093/
https://www.ncbi.nlm.nih.gov/pubmed/27076878
http://dx.doi.org/10.1016/j.csbj.2016.02.003