Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)

The interaction of asbestos fibers with macrophages generates harmful reactive oxygen species (ROS) and subsequent oxidative cell damage that are key processes linked to malignancy. Secoisolariciresinol diglucoside (SDG) is a non-toxic, flaxseed-derived pluripotent compound that has antioxidant prop...

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Detalles Bibliográficos
Autores principales: Pietrofesa, Ralph A., Velalopoulou, Anastasia, Albelda, Steven M., Christofidou-Solomidou, Melpo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813184/
https://www.ncbi.nlm.nih.gov/pubmed/26938529
http://dx.doi.org/10.3390/ijms17030322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813184/
https://www.ncbi.nlm.nih.gov/pubmed/26938529
http://dx.doi.org/10.3390/ijms17030322

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