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Probing the Ion Binding Site in a DNA Holliday Junction Using Förster Resonance Energy Transfer (FRET)

Holliday Junctions are critical DNA intermediates central to double strand break repair and homologous recombination. The junctions can adopt two general forms: open and stacked-X, which are induced by protein or ion binding. In this work, fluorescence spectroscopy, metal ion luminescence and thermo...

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Detalles Bibliográficos
Autores principales: Litke, Jacob L., Li, Yan, Nocka, Laura M., Mukerji, Ishita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813226/
https://www.ncbi.nlm.nih.gov/pubmed/26978349
http://dx.doi.org/10.3390/ijms17030366