TFE3 Alleviates Hepatic Steatosis through Autophagy-Induced Lipophagy and PGC1α-Mediated Fatty Acid β-Oxidation

Autophagy flux deficiency is closely related to the development of hepatic steatosis. Transcription factor E3 (TFE3) is reported to be a crucial gene that regulates autophagy flux and lysosome function. Therefore, we investigated the role of TFE3 in a cell model of hepatic steatosis. We constructed...

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Detalles Bibliográficos
Autores principales: Xiong, Jie, Wang, Kezhou, He, Jiangping, Zhang, Guangya, Zhang, Dandan, Chen, Fengling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813243/
https://www.ncbi.nlm.nih.gov/pubmed/26999124
http://dx.doi.org/10.3390/ijms17030387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813243/
https://www.ncbi.nlm.nih.gov/pubmed/26999124
http://dx.doi.org/10.3390/ijms17030387

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