Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis

Here, we screened a 10,371 library of diverse molecules using a drug-sensitive fission yeast strain to identify compounds which cause defects in chromosome segregation during mitosis. We identified a phosphorium-ylide-based compound Cutin-1 which inhibits nuclear envelope expansion and nuclear elong...

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Detalles Bibliográficos
Autores principales: Takemoto, Ai, Kawashima, Shigehiro A., Li, Juan-Juan, Jeffery, Linda, Yamatsugu, Kenzo, Elemento, Olivier, Nurse, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813296/
https://www.ncbi.nlm.nih.gov/pubmed/26869222
http://dx.doi.org/10.1242/jcs.181560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813296/
https://www.ncbi.nlm.nih.gov/pubmed/26869222
http://dx.doi.org/10.1242/jcs.181560

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