Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse

Monocyte-derived cells use an extracellular, acidic, lytic compartment (a lysosomal synapse) for initial degradation of large objects or species bound to the extracellular matrix. Akin to osteoclast degradation of bone, extracellular catabolism is used by macrophages to degrade aggregates of low den...

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Detalles Bibliográficos
Autores principales: Singh, Rajesh K., Barbosa-Lorenzi, Valéria C., Lund, Frederik W., Grosheva, Inna, Maxfield, Frederick R., Haka, Abigail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813320/
https://www.ncbi.nlm.nih.gov/pubmed/26801085
http://dx.doi.org/10.1242/jcs.181743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813320/
https://www.ncbi.nlm.nih.gov/pubmed/26801085
http://dx.doi.org/10.1242/jcs.181743

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