Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors

Gloeobacter violaceus ligand-gated ion channel (GLIC) has served as a valuable structural and functional model for the eukaryotic Cys-loop receptor superfamily. In Cys-loop and other receptors, we have previously demonstrated the crucial roles played by several conserved prolines. Here we explore th...

Descripción completa

Detalles Bibliográficos
Autores principales: Rienzo, Matthew, Rocchi, Angela R., Threatt, Stephanie D., Dougherty, Dennis A., Lummis, Sarah C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813548/
https://www.ncbi.nlm.nih.gov/pubmed/26668320
http://dx.doi.org/10.1074/jbc.M115.694372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813548/
https://www.ncbi.nlm.nih.gov/pubmed/26668320
http://dx.doi.org/10.1074/jbc.M115.694372

Ejemplares similares