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Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors

Gloeobacter violaceus ligand-gated ion channel (GLIC) has served as a valuable structural and functional model for the eukaryotic Cys-loop receptor superfamily. In Cys-loop and other receptors, we have previously demonstrated the crucial roles played by several conserved prolines. Here we explore th...

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Detalles Bibliográficos
Autores principales:	Rienzo, Matthew, Rocchi, Angela R., Threatt, Stephanie D., Dougherty, Dennis A., Lummis, Sarah C. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813548/ https://www.ncbi.nlm.nih.gov/pubmed/26668320 http://dx.doi.org/10.1074/jbc.M115.694372

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