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GPR21 KO mice demonstrate no resistance to high fat diet induced obesity or improved glucose tolerance
Gpr21 KO mice generated with Gpr21 KO ES cells obtained from Deltagen showed improved glucose tolerance and insulin sensitivity when fed a high fat diet. Further mRNA expression analysis revealed changes in Rabgap1 levels and raised the possibility that Rabgap1 gene may have been modified. To assess...
Autores principales: | Wang, Jinghong, Pan, Zheng, Baribault, Helene, Chui, Danny, Gundel, Caroline, Véniant, Murielle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813635/ https://www.ncbi.nlm.nih.gov/pubmed/27081476 http://dx.doi.org/10.12688/f1000research.7822.2 |
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